13th NYRA Meeting – SAVE THE DATES!

Dear NYRA member,  The 13th NYRA Meeting will be held in Sant Feliu de Guíxols, Girona, Spain, next May 9th-10th 2020, preceding the 21st European Testis Workshop (ETW). Both the NYRA Meeting and the ETW will take place at the Eden Roc Hotel, in the heart of the wonderful Costa Brava. So save the dates and join us! Run and take a look at the NYRA2020 Official Webpage for further details.  And do not miss this information! The 21st ETW will take Read more…

Complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primate

Boys receiving gonadotoxic treatment (e.g. chemo- or radiotherapy) before puberty face the possibility of being infertile when they reach adulthood due to the loss of germ cells. As mature spermatozoa are not present, the only fertility preservation strategy currently offered involves the cryopreservation of immature testis tissue (ITT) containing spermatogonial stem cells (SSCs). Auto-transplantation of cryopreserved ITT has the advantage of retaining SSCs within their niche, providing an optimal microenvironment, and is therefore a promising Read more…

12th Meeting of the Network for Young Researchers in Andrology

By CONSTANZE MARESCH It is our great pleasure to announce the 12th NYRA Meeting, that will be held in Giessen, Germany, on September 23rd – 24th 2019. This year the meeting will be held adjacent to the 6th International Workshop on Molecular Andrology (https://www.uni-giessen.de/fbz/fb11/institute/anatomie/molandrol2019) and the 50th Anniversary of the Department of Urology in Giessen. Currently we are working on an exciting and diverse programme with amazing national and international speakers for you and you Read more…

Tête-a-tête with Kyle Orwig

This time we bring an interview with the leader behind the group that recently published in Science the successful birth of Grady, the first rhesus macaque born after an autologous graft of immature testicular tissue. Professor Kyle Orwig obtained his PhD from Oregon State University in 1994. Afterwards, he completed postdoctoral training at the University of Kansas Medical Center and, in 1999, became assistant professor at the University of Pennsylvania. Nowadays, Dr Orwig is a Read more…

First live birth after autologous testicular tissue grafting in rhesus macaques

Fertility preservation in young people before gonadotoxic therapies (for cancer or other diseases) is nowadays one of the most challenging issues in reproductive biology. However, interesting breakthroughs are bringing it closer to reality. As we commented in our last post, Dr. Goossens’ group achieved complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primates. This time we would like to highlight the outstanding Science paper from Dr. Orwig’s laboratory, from the Magee-Womens Research Institute Read more…