Tête-a-tête with Julie Cocquet

By Thomas Darde Julie Cocquet Julie Cocquet obtained her PhD in molecular and cellular biology from Université de Paris in 2006. After 5 years of postdoctoral research in Dr. Paul Burgoyne’s lab (MRC – National Institute for Medical Research, London, UK), she was recruited as a junior PI by Inserm in Daniel Vaiman s research …

Read more

13th NYRA Meeting: COVID-19 Statement

By THOMAS DARDE 13th NYRA Meeting: COVID-19 Statement Due to the COVID-19 worldwide situation, for the health and safety of our attendees, the 13th NYRA Meeting has been postponed to next May 28th-30th, 2021. The event will be held in the same venue (Eden Roc Hotel, in Sant Feliu de Guíxols, Spain), preceding the rescheduled …

Read more

Tête-a-tête with Nils Lambalk

By Tiina Lehtiniemi The man in the editor’s chair The Dutch gynaecologist Nils Lambalk took over as editor-in-chief of Human Reproduction early this year. He is a gynaecologist and fertility specialist with focus on reproductive endocrinology. He has published over 100 papers and book chapters on subjects related to his research interests. We asked him …

Read more

Report on the 12th meeting of the Network for Young Researchers in Andrology (NYRA)

This year’s NYRA meeting, 23rd – 24th of September 2019, was held adjacent to the 6thWorkshop of Molecular Andrology and the 50th Anniversary of the Department of Urology in Giessen, Germany. The audience included Master students, PhD students, postdoctoral researchers and even a few group leaders. In total, our two-day seminar series was attended by 40 participants representing …

Read more

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia

By MANON OUD Approximately 1 in 6 couples is unable to conceive after one year of unprotected sexual intercourse. In roughly half of all infertility cases there is a male factor involved. Considered predominantly a genetic condition, currently the majority of patients with a severe form of infertility remains unexplained. Recently, Whitfield et al. discovered …

Read more

13th NYRA Meeting – SAVE THE DATES!

Registration Abstract submission 13th NYRA Meeting: REGISTRATION IS NOW OPEN! Due to the COVID-19 worldwide situation, for the health and safety of the attendees, the 13th NYRA Meeting has been postponed to next May 29th-30th, 2021 and will take place as a Virtual Meeting. Don’t miss this opportunity to join the young researcher community! Submitting your …

Read more

Tête-a-tête with Kyle Orwig

This time we bring an interview with the leader behind the group that recently published in Science the successful birth of Grady, the first rhesus macaque born after an autologous graft of immature testicular tissue. Professor Kyle Orwig obtained his PhD from Oregon State University in 1994. Afterwards, he completed postdoctoral training at the University …

Read more

First live birth after autologous testicular tissue grafting in rhesus macaques

Fertility preservation in young people before gonadotoxic therapies (for cancer or other diseases) is nowadays one of the most challenging issues in reproductive biology. However, interesting breakthroughs are bringing it closer to reality. As we commented in our last post, Dr. Goossens’ group achieved complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primates. …

Read more

Complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primate

Boys receiving gonadotoxic treatment (e.g. chemo- or radiotherapy) before puberty face the possibility of being infertile when they reach adulthood due to the loss of germ cells. As mature spermatozoa are not present, the only fertility preservation strategy currently offered involves the cryopreservation of immature testis tissue (ITT) containing spermatogonial stem cells (SSCs). Auto-transplantation of …

Read more