Tête-à-tête with Sandra Laurentino

We bring you the opportunity to get to know another invited speaker to the upcoming 14th NYRA Meeting in Norwich (September 19th-21st) through this ‘tête-à-tête’. Dr. Sandra Laurentino studied Biochemistry and did her PhD in Biomedicine at the University of Beira Interior in her native Portugal. Right afterwards she move to Germany to  join the …

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Tête-à-tête with Kristian Almstrup

This time we bring an interview to get to know another of our invited speakers at the 14th NYRA meeting, which will take place in Norwich from 19-21st of September 2022. Kristian Almstrup is a Senior Scientist at Copenhagen University Hospital – Rigshospitalet, where he serves as a research leader at the Department of Growth and Reproduction. …

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Building functional sperm

Many thousands of genes are required for male fertility in mammals. In the testis, these genes govern the diverse individual processes of mitosis, meiosis and spermiogenesis, which are ultimately required to generate sperm. During this latter process of spermiogenesis, round spermatids undergo a complete remodelling to generate a sperm tail for motility, sculpt the nucleus …

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Viable Offspring Derived From Single Unfertilized Mammalian Oocytes

The general understanding of fertilization is the fusion of two haploid gametes, the spermatozoon, and the oocyte, to form a diploid cell that goes through the multiple cell division and cell differentiation events of embryo development. However, recent research has pushed this understanding. Parthenogenesis, also known as virgin births, is another way of embryo development …

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Single cell sequencing enables novel insights to unravel human testicular tissue heterogeneity

Testis tissue is very complex and heterogeneous as it is made up of several somatic (Leydig, Sertoli, peritubular myoid cells and others) and germ cell types (spermatogonia, spermatocytes and spermatids). Due to the high number of different cell types, histological and molecular studies have always been challenging. As an example, the use of bulk RNA …

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World’s first approval for testicular re-implantation to restore fertility of childhood cancer survivors

Prof. Ellen Goossens from the Vrije Universiteit Brussel (VUB), in cooperation with the Universitair Ziekenhuis Brussel (UZ Brussel), received the ethical approval to re-implant previously frozen testicular tissue in male cancer survivors who lost their fertility because of childhood cancer treatments. If successful, sperm cells will develop in the implanted tissue to restorethe fertility ofthese patients. Childhood cancer survival rates …

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COST Action ANDRONET

ANDRONET, the biggest running European network in andrology, aims to increase research collaboration, education, and public awareness in male reproductive health. It was born within a social context of worst reproductive outcomes, tightly related with the male factor, in which establishing strong connections between clinicians and researchers is essential to tackle a problem with such …

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