Tête-a-tête with Nils Lambalk

By Tiina Lehtiniemi The man in the editor’s chair The Dutch gynaecologist Nils Lambalk took over as editor-in-chief of Human Reproduction early this year. He is a gynaecologist and fertility specialist with focus on reproductive endocrinology. He has published over 100 papers and book chapters on subjects related to his Read more…

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia

By MANON OUD Approximately 1 in 6 couples is unable to conceive after one year of unprotected sexual intercourse. In roughly half of all infertility cases there is a male factor involved. Considered predominantly a genetic condition, currently the majority of patients with a severe form of infertility remains unexplained. Read more…

First live birth after autologous testicular tissue grafting in rhesus macaques

Fertility preservation in young people before gonadotoxic therapies (for cancer or other diseases) is nowadays one of the most challenging issues in reproductive biology. However, interesting breakthroughs are bringing it closer to reality. As we commented in our last post, Dr. Goossens’ group achieved complete spermatogenesis in intratesticular testis tissue Read more…

Complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primate

Boys receiving gonadotoxic treatment (e.g. chemo- or radiotherapy) before puberty face the possibility of being infertile when they reach adulthood due to the loss of germ cells. As mature spermatozoa are not present, the only fertility preservation strategy currently offered involves the cryopreservation of immature testis tissue (ITT) containing spermatogonial Read more…