Fertility preservation in young people before gonadotoxic therapies (for cancer or other diseases) is nowadays one of the most challenging issues in reproductive biology. However, interesting breakthroughs are bringing it closer to reality. As we commented in our last post, Dr. Goossens’ group achieved complete spermatogenesis in intratesticular testis tissue Read more…
Boys receiving gonadotoxic treatment (e.g. chemo- or radiotherapy) before puberty face the possibility of being infertile when they reach adulthood due to the loss of germ cells. As mature spermatozoa are not present, the only fertility preservation strategy currently offered involves the cryopreservation of immature testis tissue (ITT) containing spermatogonial Read more…
The centriole is a microtubule-based organelle and typically consists of nine sets of short microtubule triplets arranged in a cylindrical structure. The centriole is surrounded by a special matrix, the pericentriolar matrix (PCM).
Since the beginning of the 20th century, attempts have been made to differentiate male germ cells into mature spermatozoa in culture