Variant PNLDC1, Defective piRNA Processing, and Azoospermia
By MANON OUD Approximately 1% of all men fail to produce sperm at all. In a recent publication in the New England Journal of Medicine, Nagirnaja and Mørup et al. demonstrate one of the causes for such complete lack of sperm production, which is called non-obstructive azoospermia. The results point to a direct mechanistic effect …