In a most recent study, Hua and colleagues have identified a rare homozygous nonsense mutation in the ACR gene as a causative factor for male infertility, specifically leading to Total Fertilization Failure (TFF) during in vitro fertilization (IVF) attempts. The findings, published in Human Reproduction, shed light on the genetic basis of TFF, offering new …
Over the last decades, mobile phones have become ubiquitously used regardless of people’s age, cultural background, gender, or geographical location. However, little is known about the impact on general fertility of the radiofrequency electromagnetic fields (RF-EMF) emitted by these devices, which can be absorbed by the human body. Specifically in the case of male fertility, …
The 15th NYRA meeting preceded the 22nd European Testis Workshop, held from June 17th to June 18th, 2023 in Montreux, Switzerland. The meeting venue was the historic Palace de Caux, a former palace hotel in the village of Caux, above Montreux on the Swiss Riviera. The event had 65 participants from various countries, including Algeria, …
Through this interview, get the opportunity to meet the most international speaker of our next meeting, coming straight from Australia! Professor Brett Nixon is a Senior Research Fellow of the National Health and Medical Research Council of Australia and a Professor of Biology at The University of Newcastle, Australia. In this position, he serves as …
You can now get a better knowledge on one of our speakers to the upcoming 15th NYRA Meeting in Caux (June 17th – 18th) through this ´tête-à-tête´. Prof. Christophe Arnoult obtained his PhD at the University of Grenoble Alpes where he is currently a head researcher at the Institute of Advanced Biosciences INSERM&CNRS (IAB). In …
Get to know another invited speaker to the upcoming 15th NYRA Meeting in Caux (June 17th-18th) through this interview. Dr. Pei-Hsuan Wu conducted her Ph.D. research with Richard Carthew at Northwestern University in Evanston (Illinois, U.S.). After receiving her Ph.D. degree in 2013, she joined Phillip Zamore’s laboratory at the RNA Therapeutics Institute at the …
Omics has been a hot topic in the 21st century; Genomics, transcriptomics, metabolomics, proteomics, lipidomics, etc. Nevertheless, omics hasn’t been without its challenges in terms of technical developments. For many scientists, the amount of data generated from most omics studies has been overwhelming. It has become indispensable in biology to have bioinformatic skills, which adds …
Sex chromosomes are important for the development of sperm and egg cells in mammals. In mice, reproductive cells start off as the same type of cell and then develop differently depending on the biological niche they are in. In the case of males (XY), primordial germ cells (PGCs) develop into sperm and in females (XX), …
For young boys with cancer or a non-malignant hematological disorder, conditioning therapy, abdominal/pelvic radiotherapy, and certain chemotherapies form a major risk for germ cell loss. Contradictory studies have investigated the direct effects of such diseases on the development of the prepubertal male gonad before mainline treatment. For health professionals to counsel pediatric patients in the …
Kodai Hirano, Yuta Nonami, Yoshiaki Nakamura, Toshiyuki Sato, Takuya Sato, Keiichiro Ishiguro, Takehiko Ogawa, *Shosei Yoshida Background Spermatogenesis in mammals is a temperature-sensitive developmental process that occurs at a few degrees below the core body temperature of 38 °C. Elevated testis temperatures disrupt spermatogenesis at various phases, leading to male infertility. Artificial cryptorchidism, which involves surgically …